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Enjoy Our Hotel's Facility in Anderson, South Carolina. Full Renovations were completed in October 2016. Located just off I-85 on Highway 81, our Holiday Inn Express® hotel is one of the most convenient places to stay among hotels in Anderson, South Carolina. Just a few minutes from an array of corporations and businesses, our hotel offers a quiet and peaceful place to stay. If you're traveling for business, you're sure to appreciate our quick access to businesses like Bosch, Milliken, Electrolux and AnMed Health. As an added benefit, we offer a well-equipped business center with copy, print, e-mail and fax services. When compared to other hotels in Anderson, South Carolina, our accommodations rank at the top with vacationing guests. Head to Lake Hartwell for fishing tournaments or a day of fun on the water. Downtown Anderson, the Anderson Jockey Lot and even Clemson University are all just minutes away. No matter what your reason for staying here is, our Highway 81 hotel is sure to please. Feel free to relax by the outdoor pool in the warmer months or burn off a few calories in the fitness center. As if this weren't enough, we also offer a delicious, free breakfast every morning with hot items like eggs, bacon or sausage and our signature cinnamon rolls, so stop in and fill up before you head to the office.